Inositol Phosphatide in Peas

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The enzymatic synthesis of inositol phosphatide.

Since the isolation of myo-inositol from biological sources over a hundred years ago, little has been reported concerning its metabolism. Experiments in nutrition have implicated inositol variously as a vitamin (1) and as a lipotropic agent (2) ; and more recently inositol has been identified as a soluble factor required for the survival of human cells grown in tissue culture (3). The presence ...

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The Biosynthesis of Free and Phosphatide Myo-inositol from Glucose by Mammalian Tissue Slices.

The abiity of the mammalian organism to carry out the conversion of D-ghlCOSC to myo-inositoll has been established in recent years (l-5). In addition, the incorporation of glucose carbon into both free and phosphatide-bound inositol and some observations on their interrelationship in organs of the rat have been reported (4). However, neither the sites of inositol biosynthesis within the organi...

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Brain diphosphoninositide, a new phosphatide having inositol metadiphosphate as a constituent.

Work from this laboratory has established that brain cephalin (1, 2) is a mixture of three different phosphatides; namely, phosphatidyl serine (3), phosphatidyl ethanolamine, and diphosphoinositide. In a preliminary note (4) it has been shown that diphosphoinositide has inositol metadiphosphate’ as a constituent. The present paper contains detailed proof of this statement and reports some other...

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Remember the monk and the peas? The story introduced school children to genetics long before the human genome made the evening news. The Augustinian monk Gregor Mendel conducted hundreds of experiments on the edible pea, crossing peas that were smooth or wrinkled, peas that grew tall or short, peas that had white or violet flowers. He found that the results of these crosses were predictable, an...

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ژورنال

عنوان ژورنال: Nature

سال: 1960

ISSN: 0028-0836,1476-4687

DOI: 10.1038/188146a0